Vol. 2, Issue 6 (2016)
Original Article - Clinical profile of alcoholic liver disease patients in a tertiary care teaching hospital and its correlation with type of alcoholic beverage consumption
Author(s): Dr. Nagamani R, Dr. Sakuntala P, Dr. Madhuri, Dr. Swapna, Dr. Sharath
Abstract: Introduction: Alcoholic liver cirrhosis is a major cause of morbidity and mortality worldwide. Various studies conducted on western populations show contradictory results on type of alcoholic beverage consumption and development of cirrhosis. South Asian populations are prone to develop ALD, and majority of population consuming country made alcoholic beverages. This study was carried out to evaluate the extent of complications and prognosis of alcoholic liver disease in the different types of alcohol beverage consuming patients. Materials and Methods: 100 patients who were admitted in Osmania General Hospital, Hyderabad, between April 2014 and April 2016, over a period of two years, were evaluated to correlate development of complications and prognostic markers (Discriminant function [DF] score, Model for end stage liver disease [MELD] score and Child-Pugh score) with different types of alcoholic beverage consumption (Country made Wine, Variable drinking). Results: Ascites was most common complication in Alcoholic liver disease patients followed by hepatic encephalopathy, upper GI bleed, renal failure and spontaneous bacterial peritonitis both of which correlated significantly with country made beverage (p< 0.05). All the prognostic markers measured correlated significantly with type of alcoholic beverage consumed (p< 0.05).